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T60202MMRi62
MMRi62, a ferroptosis inducer targeting MDM2-MDM4 (negative regulators of tumor suppressor p53). MMRi62 shows a P53-independent pro-apoptotic activity against pancreatic ductal adenocarcinoma (PDAC) cells and induce autophagy. MMRi62 inducesferroptosis, resulting in a increase of reactive oxygen and lysosomal degradation of ferritin heavy chain (FTH1). MMRi62 also leads to proteasomal degradation of mutant p53, also inhibits orthotopic xenograft PDAC mouse model in vivo with high frequency mutat
价 格:¥电议型 号:T60202产 地:中国大陆
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T9986(E/Z)-ZINC09659342(E/Z)-ZINC09659342,Inhibitor,Lbc-RhoA interaction,Ras,(E/Z)ZINC09659342,Ras superf
(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.
价 格:¥电议型 号:T9986产 地:中国大陆
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T61972Pomaglumetad methionil hydrochloride
Pomaglumetad methionine hydrochloride (LY2140023 hydrochloride) is a methionine prodrug of LY404039 with oral activity. LY404039 is a selective mGlu2/3 receptor agonist. Pomaglumetad methionil hydrochloride has research value in schizophrenia.
价 格:¥电议型 号:T61972产 地:中国大陆
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T8104Glycyl-L-valineEndogenous Metabolite,GlycylLvaline,Inhibitor,inhibit,Glycyl L valine
Glycyl-L-valine is a dipeptide composed of glycine and valine. It is an incomplete breakdown product of protein digestion or protein catabolism.
价 格:¥电议型 号:T8104产 地:中国大陆
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T9255Zolpidem tartrateZolpidem tartrate
Zolpidem is a prescription medication used for the treatment of insomnia, as well as some brain disorders. It is a short-acting nonbenzodiazepine hypnotic of the imidazopyridine class that potentiates gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, by binding to GABAA receptors at the same location as benzodiazepines.
价 格:¥电议型 号:T9255产 地:中国大陆
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TP1563Gap19myocardial,Gap19,cytoplasmic,Cx40/pannexin-1,inhibit,Gap Junction Protein,C-terminus,Gap 19,hem
Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.
价 格:¥电议型 号:TP1563产 地:中国大陆
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T9826GDC-0214GDC0214,GDC 0214
GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).
价 格:¥电议型 号:T9826产 地:中国大陆
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TN71894,6-Dibromoindole
4,6-Dibromoindole is a marine derived natural products found in Glossobalanus sp.
价 格:¥电议型 号:TN7189产 地:中国大陆
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TN7068Sinomenine N-oxideSinomenine N oxide,Sinomenine Noxide
Sinomenine N-oxide is one of the major metabolites of the cyclic metabolic mechanism of Sinomenine.
价 格:¥电议型 号:TN7068产 地:中国大陆
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T8143Bevantolol hydrochlorideBevantolol hydrochloride,Beta Receptor,Ca2+ channels,cerebral,Inhibitor,inhi
Bevantolol hydrochloride is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension.
价 格:¥电议型 号:T8143产 地:中国大陆
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TD0087LSulfo-Cy5.5 TrifluoroacetateSulfo-Cy-5.5 Trifluoroacetate,SulfoCy5.5 Trifluoroacetate,Sulfo Cy5.5 Tr
Sulfo-Cy5.5 Trifluoroacetate is a kind of cyano dye, which is very suitable for non-invasive in vivo near-infrared imaging, and is suitable for applications that require a low fluorescence background.
价 格:¥电议型 号:TD0087L产 地:中国大陆
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T7838Losartan CarboxaldehydeDuP 167,EXP-3179,DuP-167,Inhibitor,COX,AT1-R–blocking,intermediate aldehyde m
Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.
价 格:¥电议型 号:T7838产 地:中国大陆
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T8448ZSET1446ST101,Inhibitor,ST 101,Calcium Channel,Nicotinic acetylcholine receptors,Ca2+ channels,ZSET
ZSET-1446 is a T-type calcium channel activator potentially for the treatment of learning deficits in various types of Alzheimer disease (AD) models.
价 格:¥电议型 号:T8448产 地:中国大陆
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TN7110Ginsenoside Rs2Ginsenoside Rs2,Ginsenoside Rs-2
Ginsenoside Rs2 is a natural product isolated from the leaves of Panax japonicus var..
价 格:¥电议型 号:TN7110产 地:中国大陆
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TQ0289LY450108Inhibitor,inhibit,AMPA,Parkinson’s,LY 450108,depression,iGluR,LY-450108,LY450108,Ionotropic
LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson´s disease studies.
价 格:¥电议型 号:TQ0289产 地:中国大陆
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T9154Sodium taurodeoxycholate hydrateSodium taurodeoxycholate hydrate,Sodium taurodeoxycholate,inhibit,In
Sodium taurodeoxycholate hydrate has been used in a study to assess the effect of submicellar concentrations of bile salts on the lipid bilayer membrane.
价 格:¥电议型 号:T9154产 地:中国大陆
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TQ0039(±)-Zanubrutinib
(±)-Zanubrutinib is a potent and orally available Bruton´s tyrosine kinase (Btk) inhibitor that demonstrates superior oral bioavailability, achieving higher exposure and more complete target inhibi.
价 格:¥电议型 号:TQ0039产 地:中国大陆
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T7575L[Sar1, Ile8]-Angiotensin II 3TFA[Sar1, Ile8] Angiotensin II 3TFA,[Sar1, Ile8]Angiotensin II 3TFA,[Sa
[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.
价 格:¥电议型 号:T7575L产 地:中国大陆
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TN2069PicrocrocinInhibitor,Picrocrocin,antiproliferative,SKMEL-2,Apoptosis,malignant,melanoma,cells,human,
Picrocrocin is a natural product
价 格:¥电议型 号:TN2069产 地:中国大陆
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T9759MAO-B-IN-5MAO B IN 5,MAOBIN5
MAO-B-IN-5 is a potent, selective and orally active MAO-B inhibitor with an IC 50 of 0.204 μM. MAO-B-IN-5 has the research potential in Parkinson´s disease (PD) [1].
价 格:¥电议型 号:T9759产 地:中国大陆